Conference abstract
Changes in serum lipid levels in relation to height-for-age in a pediatric population in North West Cameroon
Pan African Medical Journal - Conference Proceedings. 2023:17(126).04
Jun 2023.
doi: 10.11604/pamj-cp.2023.17.126.1558
Archived on: 04 Jun 2023
Contact the corresponding author
Keywords: Serum lipids, height, children, Cameroon
Poster
Changes in serum lipid levels in relation to height-for-age in a pediatric population in North West Cameroon
Lifoter Navti1,&, Loveline Lum Niba2
1Department of Biochemistry, the University of Bamenda, Bamenda, Cameroon, 2Department of Public Health, the University of Bamenda, Bamenda, Cameroon
&Corresponding author
Introduction: information on the relationship between height and changes in serum lipids in children is scarce in Cameroon. This study aimed at assessing the association between height increase and serum lipid changes in children in the North West Region of Cameroon.
Methods: this hospital-based cross-sectional analysis included 275 males and 333 females between the ages of 5 and 16 years, recruited at the outpatient units of two hospitals in the North West Region of Cameroon. Height of the children was measured and z-scores were calculated. Total cholesterol-TC, triglycerides-TG, low-density lipoprotein cholesterol-LDL-C, and high-density lipoprotein cholesterol-HDL-C concentrations in fasting blood samples were determined by enzymatic method using an automated clinical chemistry analyzer (RX Monaco, UK). Cases were divided into quartiles of height z-score. Multiple linear regression analysis was used to compare mean lipid concentrations across quartiles of height z-score after controlling for age, body weight, systolic and diastolic blood pressure and blood glucose.
Results: from this sample, there was a significant decrease in mean TC (168.8 to 127.2mg/dl; p < 0.001), TG (99.0 to 84.1mg/dl; p = 0.019) and LDL-C (91.1 to 69.4mg/dl; p = 0.018) in boys and a significant decrease in mean TC (171.2 to 144.7mg/dl; p = 0.004) and HDL-C (62.8 to 28.7mg/dl; p < 0.001) in girls with increasing quartiles of height z-score. However, the decrease in HDL-C in boys (p = 0.053) and the decrease in TG (p = 0.211) and LDL-C (p = 0.732) in girls with increasing height were not significant.
Conclusion: serum lipids decreased with increasing height after controlling for different variables. This study indicates that short children have higher serum lipid concentrations and this may increase the risk of lipid disorders, which may persist into adulthood.
Changes in serum lipid levels in relation to height-for-age in a pediatric population in North West Cameroon
Lifoter Navti1,&, Loveline Lum Niba2
1Department of Biochemistry, the University of Bamenda, Bamenda, Cameroon, 2Department of Public Health, the University of Bamenda, Bamenda, Cameroon
&Corresponding author
Introduction: information on the relationship between height and changes in serum lipids in children is scarce in Cameroon. This study aimed at assessing the association between height increase and serum lipid changes in children in the North West Region of Cameroon.
Methods: this hospital-based cross-sectional analysis included 275 males and 333 females between the ages of 5 and 16 years, recruited at the outpatient units of two hospitals in the North West Region of Cameroon. Height of the children was measured and z-scores were calculated. Total cholesterol-TC, triglycerides-TG, low-density lipoprotein cholesterol-LDL-C, and high-density lipoprotein cholesterol-HDL-C concentrations in fasting blood samples were determined by enzymatic method using an automated clinical chemistry analyzer (RX Monaco, UK). Cases were divided into quartiles of height z-score. Multiple linear regression analysis was used to compare mean lipid concentrations across quartiles of height z-score after controlling for age, body weight, systolic and diastolic blood pressure and blood glucose.
Results: from this sample, there was a significant decrease in mean TC (168.8 to 127.2mg/dl; p < 0.001), TG (99.0 to 84.1mg/dl; p = 0.019) and LDL-C (91.1 to 69.4mg/dl; p = 0.018) in boys and a significant decrease in mean TC (171.2 to 144.7mg/dl; p = 0.004) and HDL-C (62.8 to 28.7mg/dl; p < 0.001) in girls with increasing quartiles of height z-score. However, the decrease in HDL-C in boys (p = 0.053) and the decrease in TG (p = 0.211) and LDL-C (p = 0.732) in girls with increasing height were not significant.
Conclusion: serum lipids decreased with increasing height after controlling for different variables. This study indicates that short children have higher serum lipid concentrations and this may increase the risk of lipid disorders, which may persist into adulthood.
