Conference abstract
Factors influencing blood transfusion among sick neonates at Mbingo Baptist Hospital-Kom in the North West Region, Cameroon
Pan African Medical Journal - Conference Proceedings. 2023:17(21).04
Jun 2023.
doi: 10.11604/pamj-cp.2023.17.21.1610
Archived on: 04 Jun 2023
Contact the corresponding author
Keywords: Sick neonates, blood transfusions, factors influencing
Oral presentation
Factors influencing blood transfusion among sick neonates at Mbingo Baptist Hospital-Kom in the North West Region, Cameroon
Kan Kate Mafor1,&, Ndandjock Fomenky1, Monono Naiza2, Achuasah Mesack1, Chiabi Andrea1, Mah Evelyn3
1Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon, 2Department of Internal Medicine and Paediatrics, Faculty of Health Sciences, University of Buea, Buea, Cameroon, 3Department of Paediatrics, Faculty of Biomedical and Medical Sciences, University of Yaoundé, Cameroon
&Corresponding author
Introduction: neonates especially sick and preterm babies constitute the greatest populations in most countries with high rates of blood transfusion used in the management of several medical and surgical conditions resulting in anemia. Anaemia is the commonest indication of blood transfusion among hospitalized neonates. Despite the usefulness of this intervention; blood transfusion may be being associated with serious complications both acute and chronic several factors affect the need for transfusion and early identification of these could provide knowledge on the necessary caution about actions to implement to promote or prevent this treatment modality. The objective was to determine factors influencing blood transfusions in neonates admitted at the neonatal unit of the Mbingo Baptist Hospital.
Methods: this was a case-control study carried out in the neonatal unit of the Mbingo Baptist Hospital from May 2018 to May 2022 recruiting neonates admitted during the study period. Cases were sick neonates admitted with at least a complete blood count who received blood transfused during hospitalization while controls were sick neonates with a complete blood count without blood transfusion. Neonates were matched for gestational age and consecutively recruited. Neonates excluded from the study were babies with incomplete files and those discharged against medical advice. The studied variables were demographic and perinatal factors of the neonate, clinical features and investigations were done for neonate and maternal characteristics. Data were analyzed using appropriate statistical test with significance set at p-value < 0.05 and 95% confidence interval.
Results: two hundred and eight neonates were admitted during our study period among which 55 neonates were transfused giving us a transfusion rate of 26.44%. Neonatal sepsis, congenital malformations, and blood loss from phlebotomy were factors found to positively influence blood transfusion after multivariate analysis while admission hemoglobin of the neonate at or above 15g/dl decreased the need for blood transfusion.
Conclusion: neonatal blood transfusion rate among sick babies in this study was 26.44% and was associated with neonatal sepsis, congenital malformations and excess blood loss from iatrogenic phlebotomy while high hemoglobin at admission decreased the need for blood transfusion. Recommendations: we recommend minimal blood sampling for biological investigations among hospitalized neonates and prompt treatment of neonatal sepsis to decrease rates of blood transfusion.
Factors influencing blood transfusion among sick neonates at Mbingo Baptist Hospital-Kom in the North West Region, Cameroon
Kan Kate Mafor1,&, Ndandjock Fomenky1, Monono Naiza2, Achuasah Mesack1, Chiabi Andrea1, Mah Evelyn3
1Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon, 2Department of Internal Medicine and Paediatrics, Faculty of Health Sciences, University of Buea, Buea, Cameroon, 3Department of Paediatrics, Faculty of Biomedical and Medical Sciences, University of Yaoundé, Cameroon
&Corresponding author
Introduction: neonates especially sick and preterm babies constitute the greatest populations in most countries with high rates of blood transfusion used in the management of several medical and surgical conditions resulting in anemia. Anaemia is the commonest indication of blood transfusion among hospitalized neonates. Despite the usefulness of this intervention; blood transfusion may be being associated with serious complications both acute and chronic several factors affect the need for transfusion and early identification of these could provide knowledge on the necessary caution about actions to implement to promote or prevent this treatment modality. The objective was to determine factors influencing blood transfusions in neonates admitted at the neonatal unit of the Mbingo Baptist Hospital.
Methods: this was a case-control study carried out in the neonatal unit of the Mbingo Baptist Hospital from May 2018 to May 2022 recruiting neonates admitted during the study period. Cases were sick neonates admitted with at least a complete blood count who received blood transfused during hospitalization while controls were sick neonates with a complete blood count without blood transfusion. Neonates were matched for gestational age and consecutively recruited. Neonates excluded from the study were babies with incomplete files and those discharged against medical advice. The studied variables were demographic and perinatal factors of the neonate, clinical features and investigations were done for neonate and maternal characteristics. Data were analyzed using appropriate statistical test with significance set at p-value < 0.05 and 95% confidence interval.
Results: two hundred and eight neonates were admitted during our study period among which 55 neonates were transfused giving us a transfusion rate of 26.44%. Neonatal sepsis, congenital malformations, and blood loss from phlebotomy were factors found to positively influence blood transfusion after multivariate analysis while admission hemoglobin of the neonate at or above 15g/dl decreased the need for blood transfusion.
Conclusion: neonatal blood transfusion rate among sick babies in this study was 26.44% and was associated with neonatal sepsis, congenital malformations and excess blood loss from iatrogenic phlebotomy while high hemoglobin at admission decreased the need for blood transfusion. Recommendations: we recommend minimal blood sampling for biological investigations among hospitalized neonates and prompt treatment of neonatal sepsis to decrease rates of blood transfusion.
