Conference abstract
Amplitude and factors associated with intradialytic blood pressure variability in low income setting
Pan African Medical Journal - Conference Proceedings. 2023:17(23).04
Jun 2023.
doi: 10.11604/pamj-cp.2023.17.23.1568
Archived on: 04 Jun 2023
Contact the corresponding author
Keywords: Amplitude, variation, blood pressure, hemodialysis, Douala
Oral presentation
Amplitude and factors associated with intradialytic blood pressure variability in low income setting
Ebene Mbende Romain1,&, Dzudie Anastase2,3, Fouda Hermine2,3, Mouliom Sidick1,2, Ladé Viché1,2, Kamdem Félicité1,2, Halle Marie Patrice1,2
1Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon, 2Department of Internal Medicine, Douala General Hospital, Douala, Cameroon, 3Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
&Corresponding author
Introduction: abnormal Blood pressure (BP) variability is a frequent complication during hemodialysis. Our aim was to determine the amplitude and the factors associated with intradialytic BP variability amongst patients with kidney failure on chronic hemodialysis in Cameroon.
Methods: we conducted a cross-sectional study at the Douala General Hospital. Patients aged over 18 years and on hemodialysis for more than 3 months were included, provided they give their written consent. Patients were excluded if they had an acute complication 24h before dialysis including abrupt volume depletion. Five BP measurements were taken hourly during hemodialysis. We assessed the intra-dialytic BPV using blood pressure average real variability. Values above the median were considered abnormal variations. Statistical analysis was performed using SPSS 25.0 software with significance defined as p-value < 0.05.
Results: of a total of 169 patients included, 69.23% were male. The mean age was 47.68 (13.76) years. The main comorbidities were hypertension (94.67%) and diabetes (15.98%). The median (min-max) hourly change in systolic BP was 11.50 (8.00-16.50) mmHg. Half of the patients had an abnormal amplitude of BP variation and age ≥ 70 years, high blood pressure, the use of antihypertensive medication, dialysis vintage ≥ 5 years and ultrafiltration rate ≥ 850 ml/h were independently associated with BP variability.
Conclusion: our findings suggest that patients undergoing chronic hemodialysis in our setting present with a high amplitude of variation in intradialytic systolic BP and associated factors are mainly related mainly to the patient's comorbidities and lifestyle.
Amplitude and factors associated with intradialytic blood pressure variability in low income setting
Ebene Mbende Romain1,&, Dzudie Anastase2,3, Fouda Hermine2,3, Mouliom Sidick1,2, Ladé Viché1,2, Kamdem Félicité1,2, Halle Marie Patrice1,2
1Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon, 2Department of Internal Medicine, Douala General Hospital, Douala, Cameroon, 3Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
&Corresponding author
Introduction: abnormal Blood pressure (BP) variability is a frequent complication during hemodialysis. Our aim was to determine the amplitude and the factors associated with intradialytic BP variability amongst patients with kidney failure on chronic hemodialysis in Cameroon.
Methods: we conducted a cross-sectional study at the Douala General Hospital. Patients aged over 18 years and on hemodialysis for more than 3 months were included, provided they give their written consent. Patients were excluded if they had an acute complication 24h before dialysis including abrupt volume depletion. Five BP measurements were taken hourly during hemodialysis. We assessed the intra-dialytic BPV using blood pressure average real variability. Values above the median were considered abnormal variations. Statistical analysis was performed using SPSS 25.0 software with significance defined as p-value < 0.05.
Results: of a total of 169 patients included, 69.23% were male. The mean age was 47.68 (13.76) years. The main comorbidities were hypertension (94.67%) and diabetes (15.98%). The median (min-max) hourly change in systolic BP was 11.50 (8.00-16.50) mmHg. Half of the patients had an abnormal amplitude of BP variation and age ≥ 70 years, high blood pressure, the use of antihypertensive medication, dialysis vintage ≥ 5 years and ultrafiltration rate ≥ 850 ml/h were independently associated with BP variability.
Conclusion: our findings suggest that patients undergoing chronic hemodialysis in our setting present with a high amplitude of variation in intradialytic systolic BP and associated factors are mainly related mainly to the patient's comorbidities and lifestyle.
