Conference abstract
COVID-19 vaccination: impact on disease severity and mortality at the Bamenda Regional Hospital
Pan African Medical Journal - Conference Proceedings. 2023:17(98).04
Jun 2023.
doi: 10.11604/pamj-cp.2023.17.98.1504
Archived on: 04 Jun 2023
Contact the corresponding author
Keywords: COVID-19 vaccination, severe disease, mortality
Oral presentation
COVID-19 vaccination: impact on disease severity and mortality at the Bamenda Regional Hospital
Princewill Kum Unji1,&, Alex Mambap Tatang1,2, Samuel Angwafor1,2, Loveline Lum Niba1, Adji Minette Jaqueline Porro2, Denis Nsame Nforniwe2, Andreas Chiabi1
1Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon, 2Bamenda Regional Hospital, Bamenda, Cameroon
&Corresponding author
Introduction: ending the current COVID-19 pandemic entails attaining herd immunity which requires high vaccination rates. However, vaccination rates remain very low in our setting, one reason being vaccine hesitancy from insufficient data on the benefits of vaccination. This study aimed at bridging the knowledge gap on the effect of vaccination on disease severity and mortality.
Methods: hospital-based retrospective cohort study for COVID-19 patients managed by the Bamenda Regional Hospital from the 18th August 2021 to the 28th February 2022. Regression analysis is used to assess the relationship between vaccination status and disease severity, as well as mortality.
Results: the 1389 participants included had a mean age of 49.5 (±19.5) years and a female predominance (60.2%). Overall, 81(5.8%) were fully vaccinated and 77(5.5%) partially. Also, 485(34.9%) had comorbidities, 419(30.2%) were admitted with moderate to severe disease among which 137(32.7%) died. Among patients admitted, 2(0.5%) were fully vaccinated and 6(1.4%) partially, where fully vaccinated had lower odds for severe disease (OR=0.05; CI95(0.01-0.18); p=0.000), as well as partially vaccinated (OR=0.15; CI95(0.06-0.35); p=0.000). Among the deaths, 2(1.5%) were partially vaccinated and none fully. Partial vaccination didn’t affect odds of mortality (OR=1.02; CI95(0.19-5.65); p=0.980).
Conclusion: complete vaccination, and to a lesser extent partial vaccination was associated with lower odds for severe disease. Regarding mortality, complete vaccination was suggestive of being protective while partial vaccination had no effect.
COVID-19 vaccination: impact on disease severity and mortality at the Bamenda Regional Hospital
Princewill Kum Unji1,&, Alex Mambap Tatang1,2, Samuel Angwafor1,2, Loveline Lum Niba1, Adji Minette Jaqueline Porro2, Denis Nsame Nforniwe2, Andreas Chiabi1
1Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon, 2Bamenda Regional Hospital, Bamenda, Cameroon
&Corresponding author
Introduction: ending the current COVID-19 pandemic entails attaining herd immunity which requires high vaccination rates. However, vaccination rates remain very low in our setting, one reason being vaccine hesitancy from insufficient data on the benefits of vaccination. This study aimed at bridging the knowledge gap on the effect of vaccination on disease severity and mortality.
Methods: hospital-based retrospective cohort study for COVID-19 patients managed by the Bamenda Regional Hospital from the 18th August 2021 to the 28th February 2022. Regression analysis is used to assess the relationship between vaccination status and disease severity, as well as mortality.
Results: the 1389 participants included had a mean age of 49.5 (±19.5) years and a female predominance (60.2%). Overall, 81(5.8%) were fully vaccinated and 77(5.5%) partially. Also, 485(34.9%) had comorbidities, 419(30.2%) were admitted with moderate to severe disease among which 137(32.7%) died. Among patients admitted, 2(0.5%) were fully vaccinated and 6(1.4%) partially, where fully vaccinated had lower odds for severe disease (OR=0.05; CI95(0.01-0.18); p=0.000), as well as partially vaccinated (OR=0.15; CI95(0.06-0.35); p=0.000). Among the deaths, 2(1.5%) were partially vaccinated and none fully. Partial vaccination didn’t affect odds of mortality (OR=1.02; CI95(0.19-5.65); p=0.980).
Conclusion: complete vaccination, and to a lesser extent partial vaccination was associated with lower odds for severe disease. Regarding mortality, complete vaccination was suggestive of being protective while partial vaccination had no effect.
