Conference abstract
Research questions and priorities for pediatric tuberculosis: a survey of published systematic reviews and meta-analyses
Pan African Medical Journal - Conference Proceedings. 2023:18(129).03
Oct 2023.
doi: 10.11604/pamj-cp.2023.18.129.2239
Archived on: 03 Oct 2023
Contact the corresponding author
Keywords: Systematic review, pediatric tuberculosis, research priorities
Oral presentation
Research questions and priorities for pediatric tuberculosis: a survey of published systematic reviews and meta-analyses
Thomas Achombwom Vukugah1,&, Vera Nyibi Ntoh2, Derick Akompab Akoku3, Simeo Leonie2, Amed Jacob4
1Jhpiego, Yaoundé, Cameroon, 2Elizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon, 3Department of Global Health, University of Washington, Seattle, USA, 4Atlantic International University Hawaii, USA
&Corresponding author
Introduction: advancing a research agenda designed to meet the specific needs of children is critical to ending the pediatric TB epidemic. Systematic reviews are increasingly informing policies in pediatric tuberculosis (TB) care and control. However, there is a paucity of information on pediatric TB research priorities. The objective was to identify all systematic reviews and meta-analyses about any aspect of pediatric TB from 2015 to 2021
Methods: we searched MEDLINE, EMBASE, Web of Science, and the Cochrane Library for systematic reviews and meta-analyses on any aspect related to pediatric TB published between 2015 and 2021. We used the UK Health Research Classification System (HRCS) to help us classify the research questions and priorities.
Results: in total, 29 systematic reviews, with 84 research questions, were included in this review. The four most common research topics in the area of detection were; 43.33% screening, and diagnosis of TB, 23.33% evaluation of treatments and therapeutic interventions, 13.34% TB etiology and risk factors and 13.34% prevention of disease and conditions, and promotion of well-being. The research priorities focused mainly on evaluating TB diagnosis by improving yield through enhanced specimen collection or preparation and evaluating bacteriological TB diagnostic tests. Other topics of future research were developing a treatment for TB in children and assessing the use of IPT
Conclusion: there is a need for more systematic reviews on pediatric TB. The review identified several key priorities for future pediatric TB research mainly in the domain of (1) "Detection, screening and diagnosis'', ''Development of Treatments and Therapeutic Interventions" and ''Prevention of Disease and Conditions, and Promotion of Well-Being". These domains are very relevant in the research component of the roadmap towards ending TB in children.
Research questions and priorities for pediatric tuberculosis: a survey of published systematic reviews and meta-analyses
Thomas Achombwom Vukugah1,&, Vera Nyibi Ntoh2, Derick Akompab Akoku3, Simeo Leonie2, Amed Jacob4
1Jhpiego, Yaoundé, Cameroon, 2Elizabeth Glaser Pediatric AIDS Foundation, Yaoundé, Cameroon, 3Department of Global Health, University of Washington, Seattle, USA, 4Atlantic International University Hawaii, USA
&Corresponding author
Introduction: advancing a research agenda designed to meet the specific needs of children is critical to ending the pediatric TB epidemic. Systematic reviews are increasingly informing policies in pediatric tuberculosis (TB) care and control. However, there is a paucity of information on pediatric TB research priorities. The objective was to identify all systematic reviews and meta-analyses about any aspect of pediatric TB from 2015 to 2021
Methods: we searched MEDLINE, EMBASE, Web of Science, and the Cochrane Library for systematic reviews and meta-analyses on any aspect related to pediatric TB published between 2015 and 2021. We used the UK Health Research Classification System (HRCS) to help us classify the research questions and priorities.
Results: in total, 29 systematic reviews, with 84 research questions, were included in this review. The four most common research topics in the area of detection were; 43.33% screening, and diagnosis of TB, 23.33% evaluation of treatments and therapeutic interventions, 13.34% TB etiology and risk factors and 13.34% prevention of disease and conditions, and promotion of well-being. The research priorities focused mainly on evaluating TB diagnosis by improving yield through enhanced specimen collection or preparation and evaluating bacteriological TB diagnostic tests. Other topics of future research were developing a treatment for TB in children and assessing the use of IPT
Conclusion: there is a need for more systematic reviews on pediatric TB. The review identified several key priorities for future pediatric TB research mainly in the domain of (1) "Detection, screening and diagnosis'', ''Development of Treatments and Therapeutic Interventions" and ''Prevention of Disease and Conditions, and Promotion of Well-Being". These domains are very relevant in the research component of the roadmap towards ending TB in children.
