Conference abstract
High detectable viral load among HIV treated patient snacking on sweets: a cross sectional study at Yaoundé Central Hospital
Pan African Medical Journal - Conference Proceedings. 2023:18(154).03
Oct 2023.
doi: 10.11604/pamj-cp.2023.18.154.2267
Archived on: 03 Oct 2023
Contact the corresponding author
Keywords: HIV, ARVs, nutrition, viral load
Oral presentation
High detectable viral load among HIV treated patient snacking on sweets: a cross sectional study at Yaoundé Central Hospital
Kamga Wouambo Rodrigue1,&, Fangang Fanseu2, Djouela Djoulako Paule Dana3, Kouemeni Lysette Elisabeth2, Joseph Fokam4, Kouanfack Charles5
1Division of Hepatology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany, 2Higher Institute of Health Sciences, Université des Montagnes, Bangangté, Cameroon, 3Faculty of Medicine Paris Sorbonne, Paris, France, 4Chantal BIYA International Reference Centre for research on HIV/AIDS prevention and management (CIRCB), Yaounde, Cameroon, 5Day Hospital, Central Hospital of Yaoundé, Yaoundé, Cameroon
&Corresponding author
Introduction: the effective management of HIV infection remains a worrying challenge in low and middle-income countries where equal access to a suitable balanced diet remains a major challenge. More than half of people living in sub-Saharan Africa do not have free access to a healthy diet. The objective was to have a look at the impact of dietary and nutritional profile on viral load of Pl HIV who are under antiretroviral therapy follow-up in Yaoundé.
Methods: a cross-sectional prospective study was conducted from August to September 2021. The study population consisted of people living with HIV under antiretrovirals at the Yaoundé Central Hospital. Viral load (VL) was determined by RT-qPCR. Nutritional status based on body mass index (BMI), albuminemia, and food consumption by food frequency questionnaire were assessed. For all statistical analyses, p-value < 0.05 was considered significant.
Results: out of 98 patients enrolled, the mean age was 45.86 ± 9.44 years and the mean duration on ARV drugs was 9.6±5.1 years. 51% of participants were on Tenofovir +Lamivudine + Dolutegravir (TLD), 49% on Tenofovir + lamivudine + Efavirenz (TELE) and 91.8% had an undetectable viral load (<40 copies/ml). Concerning BMI, 71.4% of participants were in the overweight/obesity range. The associated factors were gender (female, p=0.027), duration under ARV drugs (p=0.023), the regimen (TELE p=0.04; TLD p=0.046), and number of meals per day (p=0.005). Regularly snacking on sweets was associated with a detectable viral load VL>40 (p=0.047).
Conclusion: sweetened diets might harm the viral load of people living with HIV. It would therefore be important to intensify nutrition education interventions among HIV-infected people by promoting a healthy and balanced diet, less sugary, and good body mass management, particularly through regular physical activity.
High detectable viral load among HIV treated patient snacking on sweets: a cross sectional study at Yaoundé Central Hospital
Kamga Wouambo Rodrigue1,&, Fangang Fanseu2, Djouela Djoulako Paule Dana3, Kouemeni Lysette Elisabeth2, Joseph Fokam4, Kouanfack Charles5
1Division of Hepatology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany, 2Higher Institute of Health Sciences, Université des Montagnes, Bangangté, Cameroon, 3Faculty of Medicine Paris Sorbonne, Paris, France, 4Chantal BIYA International Reference Centre for research on HIV/AIDS prevention and management (CIRCB), Yaounde, Cameroon, 5Day Hospital, Central Hospital of Yaoundé, Yaoundé, Cameroon
&Corresponding author
Introduction: the effective management of HIV infection remains a worrying challenge in low and middle-income countries where equal access to a suitable balanced diet remains a major challenge. More than half of people living in sub-Saharan Africa do not have free access to a healthy diet. The objective was to have a look at the impact of dietary and nutritional profile on viral load of Pl HIV who are under antiretroviral therapy follow-up in Yaoundé.
Methods: a cross-sectional prospective study was conducted from August to September 2021. The study population consisted of people living with HIV under antiretrovirals at the Yaoundé Central Hospital. Viral load (VL) was determined by RT-qPCR. Nutritional status based on body mass index (BMI), albuminemia, and food consumption by food frequency questionnaire were assessed. For all statistical analyses, p-value < 0.05 was considered significant.
Results: out of 98 patients enrolled, the mean age was 45.86 ± 9.44 years and the mean duration on ARV drugs was 9.6±5.1 years. 51% of participants were on Tenofovir +Lamivudine + Dolutegravir (TLD), 49% on Tenofovir + lamivudine + Efavirenz (TELE) and 91.8% had an undetectable viral load (<40 copies/ml). Concerning BMI, 71.4% of participants were in the overweight/obesity range. The associated factors were gender (female, p=0.027), duration under ARV drugs (p=0.023), the regimen (TELE p=0.04; TLD p=0.046), and number of meals per day (p=0.005). Regularly snacking on sweets was associated with a detectable viral load VL>40 (p=0.047).
Conclusion: sweetened diets might harm the viral load of people living with HIV. It would therefore be important to intensify nutrition education interventions among HIV-infected people by promoting a healthy and balanced diet, less sugary, and good body mass management, particularly through regular physical activity.
