Conference abstract
Gestational hypertension and peripartum cardiomyopathy: epidemiological, clinical and evolutionary profile in the reference hospitals of Yaoundé
Pan African Medical Journal - Conference Proceedings. 2023:18(55).03
Oct 2023.
doi: 10.11604/pamj-cp.2023.18.55.2000
Archived on: 03 Oct 2023
Contact the corresponding author
Keywords: PPCM, gestational hypertension, systolic dysfunction, bromocriptine
Poster
Gestational hypertension and peripartum cardiomyopathy: epidemiological, clinical and evolutionary profile in the reference hospitals of Yaoundé
Christian Ngongang Ouankou1,&
1Faculté de Médecine des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroun
&Corresponding author
Introduction: peripartum cardiomyopathy (PPCM) is a primary dilated cardiomyopathy responsible for congestive heart failure that occurs in the last two months of pregnancy or during the first five months of postpartum. It is a rare pathology with unknown etiologies. Nevertheless, several etiopathogenic factors (gestational hypertension, black race, multiparty, and poverty). The objective was to determine the epidemiological clinical and evolutionary aspects of peripartum cardiomyopathy
Methods: we carried out a prospective descriptive study over a period of six months. It was conducted in six reference hospitals in Yaounde. The study population was made up of pregnant women with dyspnoea and women who had given birth with dyspnoea. Included all pregnant or postpartum women (from the 32nd WA to the 5th month of postpartum) who had an LVEF < 45% and/or an SF < 30% associated or not with left ventricle dilation. They were placed on treatment with a follow-up over 3 months, where they had a second cardiac ultrasound to highlight the evolutionary profile.
Results: we enrolled 10 patients from 26 women who were pregnant or had given birth and presented with dyspnoea within 6 months. The average age was 25.9 ± 4.9 years (range: 16-33 years). The history of gestational hypertension was the main predisposing factor found (50%). The echocardiographic pattern depicted a hypokinetic dilated cardiomyopathy (systolic function of 27.1 ± 10.6%). The main complications were acute pulmonary edema (60%), thromboembolic events including pulmonary embolism (10%), ischemic stroke (10%), and one death (10%). The treatment of heart failure was sometimes associated with anticoagulation (n=4); and bromocriptine (n=3).
Conclusion: PPCM is a cause of heart failure during pregnancy. It primarily arises during the postpartum period regardless of maternal age. It is a serious disease due to its (important morbi-mortality rate) and its complications, both hemodynamic and thromboembolic.
Gestational hypertension and peripartum cardiomyopathy: epidemiological, clinical and evolutionary profile in the reference hospitals of Yaoundé
Christian Ngongang Ouankou1,&
1Faculté de Médecine des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroun
&Corresponding author
Introduction: peripartum cardiomyopathy (PPCM) is a primary dilated cardiomyopathy responsible for congestive heart failure that occurs in the last two months of pregnancy or during the first five months of postpartum. It is a rare pathology with unknown etiologies. Nevertheless, several etiopathogenic factors (gestational hypertension, black race, multiparty, and poverty). The objective was to determine the epidemiological clinical and evolutionary aspects of peripartum cardiomyopathy
Methods: we carried out a prospective descriptive study over a period of six months. It was conducted in six reference hospitals in Yaounde. The study population was made up of pregnant women with dyspnoea and women who had given birth with dyspnoea. Included all pregnant or postpartum women (from the 32nd WA to the 5th month of postpartum) who had an LVEF < 45% and/or an SF < 30% associated or not with left ventricle dilation. They were placed on treatment with a follow-up over 3 months, where they had a second cardiac ultrasound to highlight the evolutionary profile.
Results: we enrolled 10 patients from 26 women who were pregnant or had given birth and presented with dyspnoea within 6 months. The average age was 25.9 ± 4.9 years (range: 16-33 years). The history of gestational hypertension was the main predisposing factor found (50%). The echocardiographic pattern depicted a hypokinetic dilated cardiomyopathy (systolic function of 27.1 ± 10.6%). The main complications were acute pulmonary edema (60%), thromboembolic events including pulmonary embolism (10%), ischemic stroke (10%), and one death (10%). The treatment of heart failure was sometimes associated with anticoagulation (n=4); and bromocriptine (n=3).
Conclusion: PPCM is a cause of heart failure during pregnancy. It primarily arises during the postpartum period regardless of maternal age. It is a serious disease due to its (important morbi-mortality rate) and its complications, both hemodynamic and thromboembolic.
