Conference abstract

Prevalence and determinants of precancerous cervical lesions among women living with HIV in consultation at the Central Hospital of Yaounde

Pan African Medical Journal - Conference Proceedings. 2023:18(70).03 Oct 2023.
doi: 10.11604/pamj-cp.2023.18.70.2024
Archived on: 03 Oct 2023
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Keywords: Pre-cancerous cervical, HIV, prevalence, determinants, Yaounde Central Hospital
Poster

Prevalence and determinants of precancerous cervical lesions among women living with HIV in consultation at the Central Hospital of Yaounde

Ntsama Nnang Cunégonde1, Beyala Landry2,&, Kouanfack Charles1,3, Zambou Ngoufack François1

1Faculty of Medicine and Pharmaceutical Sciences of the University of Dschang, Department of Biological Sciences, Dschang, Cameroun, 2Department of Health Research, M.A. SANTE (Meilleur Accès aux Soins de Santé), Yaounde, Cameroon, 3Day Hospital of the Central Hospital of Yaoundé, Yaoundé, Cameroon

&Corresponding author

Introduction: the risk of developing cervical cancer is significantly higher in women living with HIV. This study aims to determine the prevalence and determinants of precancerous lesions in women living with HIV on consultation at the Yaounde Central Hospital.

Methods: this involved a descriptive and analytic transverse study carried out at the Yaounde Central Hospital and inducting every consented woman living with HIV on consultation at the Yaounde Central Hospital. Data collection was done with the help of a pretested questionnaire (socio-demographic data, obstetrical, gynecological, and immunological). Cervical and vaginal secretions were collected and analysed by the cervical smear method. The identification of cells was done under the microscope after pap smear coloration. Data obtained was analyzed through the Cspro software version 23.0.

Results: fifty-eight (58) women participated in the study with a mean age of 44.7± 10.2 years, 53(35.8%) of these women developed pre-cancerous lesions. Among these women, 18.9% presented with low-stage intraepithelial at lesion (LSIL), and 1.4% with Atypical Squamous cells of undetermined significance (ASCUS). Most of the women infected (41.7%) belong to the age group between 55-65 years, the majority of whom were widows (41.5%) against 39.4% of married women. The frequency of cervical lesions was similar in primiparous (38.1%) and multiparous (36.1%). Patients with a detectable viral load (89.2%) presented with cervical lesions with many of them having less than 5 years of antiretroviral therapy.

Conclusion: these data confirm the susceptibility of women with HIV to develop cervical precancerous lesions and thus help motivate improved management.