Conference abstract
Anti-anemic potential of beetroot (Beta Vulgaris), pineapple (Ananas comosus) and papaya (Carica papaya) juice in phenylhydrazine-treated Wistar rats
Pan African Medical Journal - Conference Proceedings. 2023:18(82).03
Oct 2023.
doi: 10.11604/pamj-cp.2023.18.82.2036
Archived on: 03 Oct 2023
Contact the corresponding author
Keywords: Epidemic, anemia, beetroot, pineapple, papaya, hematological
Poster
Anti-anemic potential of beetroot (Beta Vulgaris), pineapple (Ananas comosus) and papaya (Carica papaya) juice in phenylhydrazine-treated Wistar rats
Marlyne-Josephine Mananga1,&
1Université de Yaounde 1, Yaounde, Cameroun
&Corresponding author
Introduction: anemia among preschool children remains a public health issue in Cameroon, particularly during epidemics. Beetroot, pineapple, and papaya are the most popular fruits and legumes with several therapeutical effects. The objective was to assess the anti-anemic potential of beetroot (Beta Vulgaris), pineapple (Ananas comosus), and papaya (Carica papaya) juice in phenylhydrazine-treated male Wistar rats.
Methods: twenty-five male rats were used. Anemic model was induced in 20 rats by daily injection with phenylhydrazine (40mg/Kg b.w) for two successive days. After one day, the rats were randomly divided into five subgroups as follows: Group A (negative healthy control), group B (untreated negative control), group C (comparative control), group D and E receiving the beetroot, pineapple, and papaya juice at 1mL and 2mL/Kg concentrations respectively. At the end of the experiment, the animals of all groups were sacrificed and blood samples were taken to determine the blood glucose, haemoglobin, and complete blood count, immunological and iron status parameters.
Results: the results showed that the beetroot, pineapple, and papaya juice significantly (P<0.05) affected the increase of the haemoglobin, complete blood count (except white blood cells and men corpuscle volume), immunological parameters (except platelet), blood glucose and iron status biomarkers as compared to the anemic untreated group. Furthermore, blood glucose level was also within the normal range as noted in control rats. The concentration that gives the best effect in increasing the haemoglobin level, haematological and immunological parameters, and iron status biomarker is 2mL/Kg of natural fruit juice.
Conclusion: the present data suggest that beetroot, pineapple, and papaya juice could be a medical alternative in the prevention and management of anemia in children, pregnant women, especially during epidemics.
Anti-anemic potential of beetroot (Beta Vulgaris), pineapple (Ananas comosus) and papaya (Carica papaya) juice in phenylhydrazine-treated Wistar rats
Marlyne-Josephine Mananga1,&
1Université de Yaounde 1, Yaounde, Cameroun
&Corresponding author
Introduction: anemia among preschool children remains a public health issue in Cameroon, particularly during epidemics. Beetroot, pineapple, and papaya are the most popular fruits and legumes with several therapeutical effects. The objective was to assess the anti-anemic potential of beetroot (Beta Vulgaris), pineapple (Ananas comosus), and papaya (Carica papaya) juice in phenylhydrazine-treated male Wistar rats.
Methods: twenty-five male rats were used. Anemic model was induced in 20 rats by daily injection with phenylhydrazine (40mg/Kg b.w) for two successive days. After one day, the rats were randomly divided into five subgroups as follows: Group A (negative healthy control), group B (untreated negative control), group C (comparative control), group D and E receiving the beetroot, pineapple, and papaya juice at 1mL and 2mL/Kg concentrations respectively. At the end of the experiment, the animals of all groups were sacrificed and blood samples were taken to determine the blood glucose, haemoglobin, and complete blood count, immunological and iron status parameters.
Results: the results showed that the beetroot, pineapple, and papaya juice significantly (P<0.05) affected the increase of the haemoglobin, complete blood count (except white blood cells and men corpuscle volume), immunological parameters (except platelet), blood glucose and iron status biomarkers as compared to the anemic untreated group. Furthermore, blood glucose level was also within the normal range as noted in control rats. The concentration that gives the best effect in increasing the haemoglobin level, haematological and immunological parameters, and iron status biomarker is 2mL/Kg of natural fruit juice.
Conclusion: the present data suggest that beetroot, pineapple, and papaya juice could be a medical alternative in the prevention and management of anemia in children, pregnant women, especially during epidemics.
