Conference abstract

Impact of Ramadan fasting on glucose variability and clinical parameters in a group of Cameroonian patients with type 2 diabetes mellitus

Pan African Medical Journal - Conference Proceedings. 2023:19(2).23 Nov 2023.
doi: 10.11604/pamj-cp.2023.19.2.2094
Archived on: 23 Nov 2023
Contact the corresponding author
Keywords: Diabetes, Ramadan fasting, glycaemic variability, hypoglycaemia, hyperglycaemia
Oral presentation

Impact of Ramadan fasting on glucose variability and clinical parameters in a group of Cameroonian patients with type 2 diabetes mellitus

Ongmeb Boli Anne1,2,&, Youssoufa Ousmane1, Mba Camille3, Djeugoue Paulette4,5, Astasselbe Abba Hadja Inna4,5, Ndi Manga Arnaud2, Jingi Ahmadou1, Ashuntantang Gloria Enow1, Mbanya Jean Claude2

1Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon, 2Endocrinology and metabolic diseases unit, Yaoundé Central Hospital, Yaoundé, Cameroon, 3Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon, 4Maroua Regional Hospital, Maroua, Cameroon, 5Faculty of Medicine and Biomedical Sciences, University of Garoua, Garoua, Cameroon

&Corresponding author

Introduction: diabetes is a global health emergency affecting more than half a billion in the world. Several changes observed during Ramadan fasting could affect patients with diabetes with possible life-threatening complications. This study aimed to evaluate the impact of Ramadan fasting on glucose variability and clinical parameters among patients with type 2 diabetes mellitus.

Methods: this was a prospective cohort study that included 22 participants aged 21 years and above who fasted Ramadan month 2023/1444H among patients followed up at the Maroua Regional Hospital. Participants were followed up for two weeks before Ramadan and during the whole month of Ramadan. Socio-demographic characteristics, clinical parameters, and daily self-monitoring of blood glucose were recorded. Data were analyzed using IBM SPSS version 26.

Results: among the participants, 12 (55.5%) were female and the mean age was 54.36±8.67 years. The median duration of diabetes was 8 (5-11) years and the mean baseline glycated hemoglobin was 10.25±2.52%. No hypoglycemia was recorded before Ramadan with otherwise 9.1% of events seen during Ramadan. The proportions of patients with hyperglycemia dropped from pre-Ramadan to the fasting period respectively from 22.7% to 9.1%. The median blood glucose was lower during Ramadan 127 (109-149) mg/dl compared to before Ramadan 170 (129-196) mg/dl (p-value<0.001 CI=95%). The blood pressure and glycated hemoglobin improved significantly after Ramadan.

Conclusion: Ramadan fasting induces greater glycemic fluctuations between days with a higher incidence of hypoglycemia. However, its practice assures better glycaemic control and a notable decrease in blood pressure.