Conference abstract
Impact of chronic consumption of a diet supplemented with 30% thermooxidisied palm oil and 10% sucrose on several morphometric and haemodynamic parameters in young rats
Pan African Medical Journal - Conference Proceedings. 2023:19(21).23
Nov 2023.
doi: 10.11604/pamj-cp.2023.19.21.2085
Archived on: 23 Nov 2023
Contact the corresponding author
Keywords: Hyperlipidic diet, rat, morphometric and haemodynamic parameters
Oral presentation
Impact of chronic consumption of a diet supplemented with 30% thermooxidisied palm oil and 10% sucrose on several morphometric and haemodynamic parameters in young rats
Nguémo Tétio Joel1,&, Wankeu-Nya Modeste1, Massoma Lembé Dieudonné1, Ateba Sylvin1, Joyce-Patrick Ebélé Dikoumé Francillian1, Kengne Tomutou Inès1, Djeumeni Néely Ornela1, Hatho Towo Hyacinthe Dominique1, Tenezogang Takoukam Christian1, Sélakong Nzékuie Quelly1, Nde Zacharie1
1Laboratory of Animal Biology and Physiology, Departments of Biology and Physiology of Animals Organisms, Faculty of Sciences, University of Douala, PO BOX 24157, Douala, Douala, Cameroon
&Corresponding author
Introduction: palm oil and sugary drinks are widely consumed in Cameroon. However, this habit is not without consequences for the various organs, leading to various changes. Thermo-oxidation of palm oil is a common household practice. However, few studies report the impact of these habits on morphometrics and haemodynamics parameters. This study aimed to assess the impact of chronic consumption of this diet on several morphometrics and haemodynamics parameters.
Methods: for this, 40 rats aged 06 weeks were divided into 02 groups of 20 rats each and fed for 12 and 16 weeks; each group was subdivided into two subgroups (n = 10) receiving the standard diet and the hyperlipidic diet respectively. Morphometric and haemodynamic parameters were measured. At the end of each diet period, the animals were sacrificed and the relative mass of some organs, the lipid profile and serum total protein levels were determined.
Results and discussion: the results obtained revealed a reduction in morphometric parameters over time and an increase in haemodynamic parameters at 6 weeks and the end of each period in the animals fed the hyperlipid diet compared with the controls. Similarly, an increase in serum levels of HDL, LDL, triglycerides, total cholesterol and total protein was noted in the groups fed the hyperlipidemic diet compared with the control groups at each period. The deterioration in the parameters assessed in this study was more significant in the animals fed the hyperlipidic diet for 16 weeks, and was thought to be due to secondary compounds produced during the thermooxidation of palm oil.
Impact of chronic consumption of a diet supplemented with 30% thermooxidisied palm oil and 10% sucrose on several morphometric and haemodynamic parameters in young rats
Nguémo Tétio Joel1,&, Wankeu-Nya Modeste1, Massoma Lembé Dieudonné1, Ateba Sylvin1, Joyce-Patrick Ebélé Dikoumé Francillian1, Kengne Tomutou Inès1, Djeumeni Néely Ornela1, Hatho Towo Hyacinthe Dominique1, Tenezogang Takoukam Christian1, Sélakong Nzékuie Quelly1, Nde Zacharie1
1Laboratory of Animal Biology and Physiology, Departments of Biology and Physiology of Animals Organisms, Faculty of Sciences, University of Douala, PO BOX 24157, Douala, Douala, Cameroon
&Corresponding author
Introduction: palm oil and sugary drinks are widely consumed in Cameroon. However, this habit is not without consequences for the various organs, leading to various changes. Thermo-oxidation of palm oil is a common household practice. However, few studies report the impact of these habits on morphometrics and haemodynamics parameters. This study aimed to assess the impact of chronic consumption of this diet on several morphometrics and haemodynamics parameters.
Methods: for this, 40 rats aged 06 weeks were divided into 02 groups of 20 rats each and fed for 12 and 16 weeks; each group was subdivided into two subgroups (n = 10) receiving the standard diet and the hyperlipidic diet respectively. Morphometric and haemodynamic parameters were measured. At the end of each diet period, the animals were sacrificed and the relative mass of some organs, the lipid profile and serum total protein levels were determined.
Results and discussion: the results obtained revealed a reduction in morphometric parameters over time and an increase in haemodynamic parameters at 6 weeks and the end of each period in the animals fed the hyperlipid diet compared with the controls. Similarly, an increase in serum levels of HDL, LDL, triglycerides, total cholesterol and total protein was noted in the groups fed the hyperlipidemic diet compared with the control groups at each period. The deterioration in the parameters assessed in this study was more significant in the animals fed the hyperlipidic diet for 16 weeks, and was thought to be due to secondary compounds produced during the thermooxidation of palm oil.
