Conference abstract
Prevalence and factors associated with peripheral artery disease in type 2 diabetes mellitus patients: the case of the Bamenda Regional Hospital
Pan African Medical Journal - Conference Proceedings. 2023:19(7).23
Nov 2023.
doi: 10.11604/pamj-cp.2023.19.7.2096
Archived on: 23 Nov 2023
Contact the corresponding author
Keywords: Peripheral artery disease, diabetes mellitus, prevalence, ankle-brachial index
Oral presentation
Prevalence and factors associated with peripheral artery disease in type 2 diabetes mellitus patients: the case of the Bamenda Regional Hospital
Ongmeb Boli Anne1,2,&, Yemlu Napoleon Ngafi1, Koeke Manyim Florence1, Feutseu Charly3, Ndi Manga Arnaud2, Jingi Ahmadou1, Laah Njoyo Sylvain1, Ashuntantang Gloria Enow1,4
1Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon, 2Endocrinology and Metabolic Diseases Unit, Yaoundé Central Hospital, Yaoundé, Cameroon, 3Laboratory for Molecular Medicine and Metabolism, Biotechnology Centre, University of Yaoundé 1, Yaoundé, Cameroon, 4Internal Medicine Unit, General Hospital, Yaoundé, Cameroon
&Corresponding author
Introduction: peripheral artery disease (PAD) is a chronic occlusive arterial disease of the lower extremities caused by atherosclerosis. Over 202 million people in the world live with PAD and diabetes increases the risk of PAD up to seven-fold. PAD alone significantly impacts morbidity and mortality in people with diabetes mellitus (DM), sometimes leading to leg ulcers and amputations. There is a paucity of data on the burden of PAD in type 2 diabetes mellitus (T2DM) patients in the North West Region of Cameroon. The study was carried out to determine the prevalence and associated factors of PAD in T2DM patients at the Bamenda Regional Hospital.
Methods: the cross-sectional study was carried out at the hypertension and diabetes outpatient clinic of the Bamenda Regional Hospital. We included all consenting T2DM patients and excluded patients with significant leg ulcers and or pedal edema. For each participant, an interview and consultation of their medical records were carried out to obtain their socio-demographic data and comorbidities. Physical examination including the measurement of the ankle-brachial index (ABI) was performed to diagnose PAD, defined as ankle-brachial index (ABI) of < 0.9. Data analysis was done using IBM-SPSS version 26.0. Ethical clearance was obtained from the institutional review board of the University of Bamenda.
Results: we screened 102 subjects with a mean age (SD) of 56.17 (12.63) years and 33 (32.4%) were males. The prevalence of PAD was 18.6% (n=19) with 73.7% (n=14) mild PAD, and 26.3% (n=5) moderate form of the disease, according to the American College of Cardiology and the American Heart Association classification. Age ≥ 75 years (aOR=37.7 (3.0-390.4), p=0.044) and a past history of hypertension (aOR=4.2 (1.5-44.7), p=0.014) were independent factors associated with PAD.
Conclusion: the prevalence of PAD in T2DM is high and we recommend regular screening in our setting.
Prevalence and factors associated with peripheral artery disease in type 2 diabetes mellitus patients: the case of the Bamenda Regional Hospital
Ongmeb Boli Anne1,2,&, Yemlu Napoleon Ngafi1, Koeke Manyim Florence1, Feutseu Charly3, Ndi Manga Arnaud2, Jingi Ahmadou1, Laah Njoyo Sylvain1, Ashuntantang Gloria Enow1,4
1Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon, 2Endocrinology and Metabolic Diseases Unit, Yaoundé Central Hospital, Yaoundé, Cameroon, 3Laboratory for Molecular Medicine and Metabolism, Biotechnology Centre, University of Yaoundé 1, Yaoundé, Cameroon, 4Internal Medicine Unit, General Hospital, Yaoundé, Cameroon
&Corresponding author
Introduction: peripheral artery disease (PAD) is a chronic occlusive arterial disease of the lower extremities caused by atherosclerosis. Over 202 million people in the world live with PAD and diabetes increases the risk of PAD up to seven-fold. PAD alone significantly impacts morbidity and mortality in people with diabetes mellitus (DM), sometimes leading to leg ulcers and amputations. There is a paucity of data on the burden of PAD in type 2 diabetes mellitus (T2DM) patients in the North West Region of Cameroon. The study was carried out to determine the prevalence and associated factors of PAD in T2DM patients at the Bamenda Regional Hospital.
Methods: the cross-sectional study was carried out at the hypertension and diabetes outpatient clinic of the Bamenda Regional Hospital. We included all consenting T2DM patients and excluded patients with significant leg ulcers and or pedal edema. For each participant, an interview and consultation of their medical records were carried out to obtain their socio-demographic data and comorbidities. Physical examination including the measurement of the ankle-brachial index (ABI) was performed to diagnose PAD, defined as ankle-brachial index (ABI) of < 0.9. Data analysis was done using IBM-SPSS version 26.0. Ethical clearance was obtained from the institutional review board of the University of Bamenda.
Results: we screened 102 subjects with a mean age (SD) of 56.17 (12.63) years and 33 (32.4%) were males. The prevalence of PAD was 18.6% (n=19) with 73.7% (n=14) mild PAD, and 26.3% (n=5) moderate form of the disease, according to the American College of Cardiology and the American Heart Association classification. Age ≥ 75 years (aOR=37.7 (3.0-390.4), p=0.044) and a past history of hypertension (aOR=4.2 (1.5-44.7), p=0.014) were independent factors associated with PAD.
Conclusion: the prevalence of PAD in T2DM is high and we recommend regular screening in our setting.
